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A complex mechanistic lung model
Chumchal, Ondřej ; Mišík, Ondrej (referee) ; Jedelský, Jan (advisor)
This bachelor thesis looks at review of published airway models, with purpose of finding best avaliable solution for extension of current BUT model, reaching 7th generation of branching. The main purpose of the thesis is expanding model further into lower generations. Secondly, it deals with possibilities of getting more realistic results by coming with influence of temperature and humidity. Two main approaches were chosen, which shall be further more explored and adopted into use in BUT model, those are glass bead and rod model. In order to make model as realistic as possible, dimensionless characteristics such as Reynolds number and ratio of inner surface and volume of each generation were calculated to match those in real human lungs. The thesis concerns expansion down to 12th generation. Further calculation of deposition and flow parametres should be done, in order to verify mentioned approach.
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A complex mechanistic lung model
Chumchal, Ondřej ; Mišík, Ondrej (referee) ; Jedelský, Jan (advisor)
This bachelor thesis looks at review of published airway models, with purpose of finding best avaliable solution for extension of current BUT model, reaching 7th generation of branching. The main purpose of the thesis is expanding model further into lower generations. Secondly, it deals with possibilities of getting more realistic results by coming with influence of temperature and humidity. Two main approaches were chosen, which shall be further more explored and adopted into use in BUT model, those are glass bead and rod model. In order to make model as realistic as possible, dimensionless characteristics such as Reynolds number and ratio of inner surface and volume of each generation were calculated to match those in real human lungs. The thesis concerns expansion down to 12th generation. Further calculation of deposition and flow parametres should be done, in order to verify mentioned approach.
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